Core/Shell nanostructured material material with desirable function
In the field of biomedicine, nanoparticles are used as efficient diagnostic and therapeutic tools to detect and treat human diseases, but the small size of the nanoparticles typically less than 100 nm has generated greater concerns in terms of risks to human health and the environments. Also, such nanoparticles are water-immiscible and not sufficiently stable for biomedical applications. Therefore, the development of a method for modifying the surface of these nanoparticles in order to endow them is essential for extensive biomedical use. Among various surface modification methods, silica coating and PEGylation can be provided the advanced biocompatibility, water-dispersibility and stability in an aqueous media. Additionally, we have been applied as fluorescent probes for cell labeling in optical imaging.
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